Brain-Derived Neurotrophic factor is vital for long-term memory. The brain retains the capability of neurogenesis which is the capability to grow neurons from stem cells, even though most human neurons have prenatal formation.
 
BDNF biomarker is one of the neurotropin, which are proteins that aid the stimulation of neurogenesis. Other researched BDNF functions and affects include synaptic plasticity, inflammation and immunity, growth of cardiac and endothelial cells, lipid metabolism etc. Specific exercises, such as treadmill in mice and aerobics in humans, are considered to increase BDNF growth factors.